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Team:Tyngsboro MA Tigers
From 2012hs.igem.org
- a team description
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Example: 2012hs.igem.org/Team:Tyngsboro_MA_Tigers/Our_Pets
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Tell us more about your project. Give us background. Use this as the abstract of your project. Be descriptive but concise (1-2 paragraphs) | File:Tyngsboro MA Tigers team.png Your team picture |
| Team Tyngsboro_MA_Tigers |
| Official Team Profile |
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Contents |
Team
We're the twelve-strong inaugural Tiger Squad at Tyngsborough High School in Tyngsborough, Massachusetts, with a real interest in using our science knowledge to help the community and learn about synthetic biology along the way!
Kathleen Barrett (Liaison)
Mia Pavao (Secretary)
Lizzy Seltz (Lab Manager)
Michael Sheets (Media Specialist)
Elizabeth Barrett (Public Relations)
Madison Vigneault (Treasurer)
Taylor Vigneault (Treasurer)
Project
The Problem:
A colorless, odorless, and soundless killer takes the lives of nearly 2,100 innocent United States citizens every year; that is an average of 3 people every day. CO poisoning is the leading cause of unintentional poisoning deaths in the United States and 1 in every 2,400 people falls victim to CO poisoning. Males are 2.3 times more likely to die from CO poisoning than females and people over the age of 65 have the highest risk of dieing from the silent killer. Only by being aware of the grave danger, and understanding the structure and works of the gas, we can create a circuit giving a scent to CO.
Citation- "Carbon Monoxide Poisoning Statistics." Christensen Law Firm. 03 Sept. 2010. Web. 1 Mar. 2012. [<http://www.utahpersonalinjurylawfirm.com/2010/09/carbon-monoxide-poisoning-statistics/>].
Our Idea:
We are looking to develop a genetic circuit for bacteria that converts the odorless carbon monoxide into a malodorous output. Coupled with the common household detector, we might be able to reduce even further CO-related deaths.
R. rubrum:
Rhodospirillum rubrum is a bacterium that uses carbon monoxide as an energy source. R. rubrum has a carbon monoxide-sensing protein called CooA. In our research on R. rubrum, we found that a Turkey iGEM team in the 2010 college division developed CooA and CooA-responsive promoter biobricks they wanted make to transform into E. coli. They were able to successfully build these parts, and now our goal is to try and put them into our own genetic circuit that, in the presence of carbon monoxide, will output an unpleasant warning smell.
Our genetic circuit:[br]
Notebook
Show us how you spent your days.
Results/Conclusions
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Safety
File:Safety Contract-1.pdf What safety precautions did your team take? Did you take a safety training course? Were you supervised at all times in the lab?
Attributions
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Human Practices
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Fun!
What was your favorite team snack?? Have a picture of your team mascot?
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