Team:Lethbridge Canada

From 2012hs.igem.org

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You are provided with this team page template with which to start the iGEM season.  You may choose to personalize it to fit your team but keep the same "look." Or you may choose to take your team wiki to a different level and design your own wiki.  You can find some examples <a href="http://2009.igem.org/Help:Template/Examples">HERE</a>.
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You <strong>MUST</strong> have the following information on your wiki:
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<ul style="font-weight:normal;">
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<li>a team description</li>
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<li>project description</li>
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<li>safety information (did your team take a safety training course? were you supervised in the lab?)</li>
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<li>team attribution (who did what part of your project?)</li>
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REMEMBER, keep all of your pages within your teams namespace. <br><span style="font-weight:normal; font-style:italic;">Example: 2012hs.igem.org/Team:Lethbridge_Canada/Our_Pets</span>
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{| style="color:#000000;background-color:#b5cde2;" cellpadding="6" cellspacing="3" border="0" bordercolor="#00FFFF" width="65%" align="center"
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{| style="color:#000000;background-color:#b5cde2;" cellpadding="6" cellspacing="3" border="0" bordercolor="#00FFFF" width="65%" align="center"
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!align="center"|[[Home]]
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!align="center"|[[The Team]]
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!align="center"|[[The Project]]
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|You can write a background of your team here.  Give us a background of your team, the members, etc.  Or tell us more about something of your choosing.
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!align="center"|[[Results]]
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|[[Image:Lethbridge_Canada_logo.png|200px|right|frame]]
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!align="center"|[[Human Practices]]
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!align="center"|[[Notebook]]
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!align="center"|[[Safety]]
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''Tell us more about your project.  Give us background.  Use this as the abstract of your project.  Be descriptive but concise (1-2 paragraphs)''
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|[[Image:Lethbridge_Canada_team.png|right|frame|Your team picture]]
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|align="center"|[[Team:Lethbridge_Canada | Team Lethbridge_Canada]]
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{| style="color:#1b2c8a;background-color:#0c6;" cellpadding="3" cellspacing="1" border="1" bordercolor="#fff" width="62%" align="center"
 
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!align="center"|[http://igem.org/Team.cgi?year=2012&division=high_school&team_name=Lethbridge_Canada Official Team Profile]
 
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===Team===
 
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Tell us about your team, your school!
 
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===Project===
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What are you working on this semester?
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===Notebook===
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== '''Introduction''' ==
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Show us how you spent your days.
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===Results/Conclusions===
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| Insulin is a hormone produced by pancreatic beta cells that causes cell membranes to become more permeable to glucose. It helps regulate blood sugar levels in the body; more is secreted as more sugar enters the bloodstream after a meal is consumed. Insulin and glucagon (another pancreatic hormone that increases blood sugar levels) are partners in the negative feedback loop that control the body’s blood sugar concentration.
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What did you achieve over the course of your semester?
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===Safety===
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Diabetes mellitus is a disease that is characterized by abnormally high blood glucose concentrations.  Animal cells need glucose for energy, and these cells absorb glucose from the bloodstream with the help of insulin. Diabetes mellitus occurs when the immune system attacks and destroys the pancreatic beta cells that produce insulin so not enough is produced (type 1) or when the body’s cells become resistant to the action of insulin (type 2).
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What safety precautions did your team take? Did you take a safety training course? Were you supervised at all times in the lab?
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===Attributions===
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Our goal is to use the natural glucose detecting mechanism found in Escherichia coli and combine it with the human insulin producing gene to create a “prosthetic” pancreatic beta cell. The transcription of insulin will only begin when a change in glucose levels in the cell’s external environment stimulates a sensory transduction chain of events.There are two parts to our project:
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Who worked on what?
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1) Construct 1 focuses on the glucose sensing mechanism.
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===Human Practices===
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2) Construct 2 focuses on insulin production and release.
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===Fun!===
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What was your favorite team snack?? Have a picture of your team mascot?
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== '''Sponsors''' ==
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<forum_subtle />
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| Gold Sponsor:  [[Image:iitbombaylogo.jpg]]                            Silver Sponsors:  [[Image:DSIR LOGO1.jpg]]
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Revision as of 00:57, 27 May 2012

000.jpg
Home The Team The Project Results Human Practices Notebook Safety



Introduction

Insulin is a hormone produced by pancreatic beta cells that causes cell membranes to become more permeable to glucose. It helps regulate blood sugar levels in the body; more is secreted as more sugar enters the bloodstream after a meal is consumed. Insulin and glucagon (another pancreatic hormone that increases blood sugar levels) are partners in the negative feedback loop that control the body’s blood sugar concentration.


Diabetes mellitus is a disease that is characterized by abnormally high blood glucose concentrations. Animal cells need glucose for energy, and these cells absorb glucose from the bloodstream with the help of insulin. Diabetes mellitus occurs when the immune system attacks and destroys the pancreatic beta cells that produce insulin so not enough is produced (type 1) or when the body’s cells become resistant to the action of insulin (type 2).


Our goal is to use the natural glucose detecting mechanism found in Escherichia coli and combine it with the human insulin producing gene to create a “prosthetic” pancreatic beta cell. The transcription of insulin will only begin when a change in glucose levels in the cell’s external environment stimulates a sensory transduction chain of events.There are two parts to our project:

1) Construct 1 focuses on the glucose sensing mechanism.

2) Construct 2 focuses on insulin production and release.

Sponsors

Gold Sponsor: File:Iitbombaylogo.jpg Silver Sponsors: File:DSIR LOGO1.jpg