Team:SouthBendMishawakaIN

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!align="center"|[[Team:SouthBend-Mishawaka-HS|<font color=#99FFFF >Home</font>]]
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!align="center"|[[Team:SouthBend-Mishawaka-HS/Team|<font color=#99FFFF >The Team</font>]]
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!align="center"|[[Team:SouthBend-Mishawaka-HS/Project|<font color=#99FFFF >The Project</font>]]
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DNA Arcitects
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SouthBendMishawakaIN
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Team: SouthBendMishawakaIN
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Title: The "Arsenator:" Design and development of a biosensor for arsenic in ground water
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<h4>Abstract</h4>
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Millions of people worldwide are exposed to toxic levels of arsenic through contaminated
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drinking water.  In last year’s project, we began the development of an E. coli-based
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arsenic biosensor using an arsenic-induced promoter from the Registry (K190015).  Like the
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Groningen Team, we found that this promoter is “leaky,” having a constant low level of
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activity.  We explored ways of reducing background activity to improve the sensitivity of
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our device.  We have built and characterized biosensors using K190015 and a number of
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chemiluminescence generators from Vibrio fisheri and two species of fireflies.  In order to
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standardize our biosensor we have designed and built a simple luminometer.  Paired with our
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device, this can be used to inexpensively and rapidly detect arsenic in water, even by
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people in underdeveloped parts of the world.
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Revision as of 20:16, 14 June 2012

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